ThinksMarkedly wrote:Francesca Simões appears to be an exception, not the rule, to the regular genetic uplift program. She was clearly an experimental project, which means she was conceived via carefully selected gametes and probably received genetic treatment to make the genes exist and express themselves. We're also told she was given to Dr. Simões and his wife for raising.
tlb wrote:Perhaps not as much an exception as you think: I believe we are told that the Bardasano line was developed in vitro, also the Detweiler line. A case of cloning with modifications. Yes, the LRPB was interested in what random biology might turn up; but there was also a lot of gene editing going on.
ThinksMarkedly wrote:Let me be more specific: I do think in vitro conception and eugenetic selection of partners is widespread and commonplace in the MAlign, in all Star Lines. Moreover, splicing of proven sequences is probably done in all of them too, with more effort on Alphas than Gammas, at the time of conception.
Francesca was special because her traits were highly experimental. So she really had no parents and had to be raised by a couple who would give her the education and upbringing a child needs. There's only so much you can glean from humans raised as "lab animals," since they'll never be productive members of society.
Bardasano appears to be a similar, if not as extreme case. She seems to have experimental qualities, as we've seen text talking about how a new iteration/generation of Bardasanos might need adjustments. She was probably conceived in vitro from selected gametes and then raised by a suitable family.
The Detweilers are unlikely to be such a case. Their genetic code probably contains only the most proven traits and if it were not for the fact that there were six of them, Albrecht and Evie might have raised in their own household. As it was, four to six of them were probably raised by "noble" families until early adulthood. And if there's any thing that they are experimented on is the combination of certain traits that are reserved exclusively to them. Because of course they have done that. But Albrecht himself may have been a "normal" child, raised by *Zebediah Detweiler.
And that's what I expect happens to the majority of the Star Lines.
* unattested. The letter before A, if you wrap around the alphabet, is Z. Unless they use the Norwegian alphabet, in which case it might have been Åsbjørn Detweiler.
This does not really answer the question, but I thought it is germane. The issue is that in order to be able to talk about a Detweiler or Bardasano line, then the inclusion of genetic material has to be controlled. Cthia and I had an argument about this some years ago, because he believed each generation involved the normal mingling of the DNA of two people; which would dilute the contribution of the named ancestor. I insisted that modifications done in the lab, could preserve the distinction.
In
Detweiler Vision vs Beowulf Code: "Right" and "Wrong" RFC wrote:
The Beowulf code is entirely prepared for genetic modification to deal with recognized disease states, and within the limits of the donor genetic material which is combined to create a human being, the Beowulf code is prepared to allow the parents to mitigate what they — the parents — see as undesirable characteristics and to enhance what they — the parents — see as desirable characteristics. There are some mods that a Beowulfan geneticist would not be prepared to perform, whatever the parents desired, however. For example, Beowulf’s experience with the consequences of enhancing human intelligence has indicated that beyond a certain point, the negative personal and societal consequences rapidly begin exceeding the positive ones. Both the Meyerdahl and the Wynton genetic mods included a sort of general intelligence enhancement, but not something that was designed to produce cognitive geniuses or idiot savants. It was, if you will, a generalist enhancement, which still carries what some people would argue are some potentially hefty negative consequences. What happened with Francesca Simoes is an example of the sort of direct, immediate, severely negative consequences Beowulf is unprepared to risk in the pursuit of greater — or more "targeted" — intellectual improvement. There are are bunches and bunches of less immediately negative consequences which have been well documented, not simply on Beowulf but in other places in the galaxy’s medical literature. The Alignment is prepared to accept those negative consequences in order to enhance specific desired consequences, and to cull dramatic failures (like Francesca) or entire lines (as almost happened to the Bardasano line) if it proves less than satisfactory or dangerously unreliable (to the Alignment and its purposes). At the same time, the Alignment is prepared to tolerate highly negative consequences — like a taste for sadism slaked using genetic slaves — if that seems advantageous to its purposes. This means, on the one hand, that the Alignment is prepared to “throw away” its mistakes, whereas Beowulf argues that medical ethics preclude the pursuit of a desired outcome at the likely cost of being compelled to decide to cull an individual or an entire line of individuals. On the other hand, the Alignment is prepared to build in negatives in order to achieve positives (as defined by the Alignment), which reminds Beowulf all to clearly of the Asian super soldiers of the Final War.
--- snip --
Since I’ve already wandered somewhat afield from the topic I originally set out to discuss, I should also point out that Albrecht Detweiler and his sons are not clones of Leonard Detweiler. They are, in effect, the current generation of the steadily improved Detweiler genotype. Remember we’re talking about a prolong society here, and the actual age difference between Albrecht and Benjamin isn’t very great for that sort of society. Nor are the offspring of the Detweiler “sons” genetic duplicates of their parents. Albrecht was cloned, frankly, because by all of the tests the Alignment could apply, he was going to be an incredibly capable generalist and leader and the Long-Range Planning Board decided that given how far into the endgame of the Alignment’s strategy they were, it made a great deal of sense to provide an entire cohort of equally capable leaders to whom Albrecht could delegate areas of responsibility.
From
Torch of Freedom, chapter 17:
Bardasano nodded, although her own expression didn't even flicker. Of course, she represented one of Long-Range Planning's in vitro lines, McBryde reminded himself, and one which had been culled more than once, itself. For that matter, at least one of her own immediate clones had been culled, and not until late adolescence, at that, if he remembered correctly. Still, while the culled Bardasano had been the next best thing to a genetic duplicate to Isabel (not quite; there'd been a few experimental differences, of course), it had scarcely been what the word "brother" or "sister" would have implied to a man like Jack McBryde. Like a lot—even the majority—of LRPB's in vitro children, she'd been tube-birthed and crèche-raised, not placed in a regular family environment or encouraged to form sibling bonds with her fellow clones. No one had ever officially told McBryde anything of the sort, but he strongly suspected that lack of encouragement represented a deliberate policy on the Board's part—a way to avoid the creation of potentially conflicting loyalties. So maybe this was simply too far outside her own experience for her to have more than a purely intellectual appreciation for Herlander Simões' anguish.